MIR-200A ATTENUATED OXIDATIVE STRESS, INFLAMMATION, AND APOPTOSIS IN DEXTRAN SULFATE SODIUM-INDUCED COLITIS THROUGH ACTIVATION OF NRF2

miR-200a attenuated oxidative stress, inflammation, and apoptosis in dextran sulfate sodium-induced colitis through activation of Nrf2

IntroductionOxidative stress and inflammatory responses are critical factors in ulcerative colitis disease pathogenesis.Nuclear factor erythroid 2-related factor Hutch 2 (Nrf2) modulates oxidative stress and suppresses inflammatory responses, and the protective benefits of Nrf2 activation have been associated with the therapy of ulcerative colitis.

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Identification of novel variants of metadherin in breast cancer.

Metadherin (MTDH, also known as AEG-1, and Lyric) has been demonstrated to play a potential role in several significant aspects of tumor progression.It has been reported that overexpression of MTDH is associated with progression of disease and poorer prognosis in breast cancer.However, there are no studies to date assessing variants of the MTDH gen

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